Best Dispensaries Near Me in Mesilla, New Mexico
Top 30 best dispensaries in Mesilla, NM — ranked by WeedDispos Score.
Last updated October 2026 · rankings refreshed Oct 30, 2026 · 56 licensed stores tracked near Mesilla · 13,962 reviews
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Quick answer
The best dispensaries in Mesilla, NM are Greene Street Weed Dispensary, PurLife Dispensary - Las Cruces and Top Crop Cannabis Co. — chosen from 56 licensed stores, average rating 4.8★.
Rankings come from the WeedDispos Score — a 0–100 composite of review rating, review volume and recency, listing completeness, verification, live menu data and photo coverage.
Mesilla dispensaries compared
| # | Dispensary | Score | Rating | Reviews | Price | Licence | Hours listed | Standout brands |
|---|---|---|---|---|---|---|---|---|
| 1 | Greene Street Weed Dispensary | 73 | 4.9★ | 758 | $ | — | Yes | — |
| 2 | PurLife Dispensary - Las Cruces | 74 | 4.8★ | 3,023 | $ | — | Yes | — |
| 3 | Top Crop Cannabis Co. | 74 | 4.8★ | 796 | $ | — | Yes | — |
| 4 | Pecos Valley Production - Dispensary & Wholesale | 73 | 4.8★ | 660 | $ | — | Yes | — |
| 5 | Munchiez Cannabis Dispensary Las Cruces | 73 | 4.9★ | 625 | $ | — | Yes | — |
| 6 | Effy Exotics Dispensary & New 24hr Drive Thru | 72 | 4.9★ | 503 | $ | — | Yes | Dime Industries, Bloom, Cure INJOY |
| 7 | Urban Wellness Cannabis Dispensary - Las Cruces | 72 | 4.9★ | 261 | $ | — | Yes | Wyld, Dime Industries, Wana Edibles |
| 8 | Akeso Botanicals LLC | 72 | 5.0★ | 167 | $ | — | Yes | — |
| 9 | Connoisseur Cannabis LLC | 72 | 5.0★ | 162 | $ | — | Yes | — |
| 10 | Pharmtrue Cannabis Dispensary - Valley | 72 | 4.8★ | 720 | $ | — | Yes | — |
| 11 | Cannaverse | 71 | 4.8★ | 315 | $ | — | Yes | Bonanza Cannabis Company, Sinful Beverages, Sublime |
| 12 | Score 420 Las Cruces | 71 | 4.8★ | 537 | $ | — | Yes | — |
| 13 | Happy Panda Cannabis Company | 70 | 4.9★ | 272 | $ | — | Yes | — |
| 14 | Dreamz Dispensary - Medical & Recreational Marijuana Cannabis Dispensary Las Cruces, NM | 70 | 4.8★ | 374 | $ | — | Yes | — |
| 15 | Amigos Cannabis Dispensary - Las Cruces | 69 | 4.8★ | 336 | $ | — | Yes | Wyld, Dime Industries, Wana Edibles |
| 16 | Vibes Cannabis LLC | 69 | 5.0★ | 150 | $ | — | Yes | — |
| 17 | Canna Company- Las Cruces Dispensary | 69 | 4.9★ | 260 | $ | — | Yes | — |
| 18 | Pecos Valley Production - Dispensary & Wholesale | 68 | 4.5★ | 882 | $ | — | Yes | — |
| 19 | Dispensary Near Me | 68 | 4.7★ | 147 | $ | — | Yes | — |
| 20 | The Matchbox | 68 | 4.8★ | 200 | $ | — | Yes | — |
| 21 | R.Greenleaf Las Cruces - Cannabis Dispensary | 67 | 4.5★ | 507 | $ | — | Yes | — |
| 22 | Round House Reserve | 67 | 4.8★ | 252 | $ | — | Yes | — |
| 23 | Simply Baked | 67 | 5.0★ | 81 | $ | — | Yes | Wyld, Dime Industries, Wana Edibles |
| 24 | BOGO Dispensary | 67 | 4.7★ | 240 | $ | — | Yes | — |
| 25 | Budz Cannabis | 66 | 4.8★ | 75 | $ | — | Yes | — |
| 26 | Everest Las Cruces North | 66 | 4.7★ | 101 | $ | — | Yes | — |
| 27 | Cloud 9 Cannabis Co. | 65 | 4.7★ | 95 | $ | — | Yes | — |
| 28 | The Kush House Cannabis Company | 65 | 4.6★ | 134 | $ | — | Yes | — |
| 29 | Yucca Point Dispensary City of Las Cruces | 65 | 4.8★ | 87 | $ | — | Yes | Crystal Collection |
| 30 | Alter Ego Dispensary | 64 | 4.8★ | 202 | $ | — | Yes | — |
Top 30 best dispensaries in Mesilla, NM
- 0.0 mi4.9(758)
Ranks on 4.9-star average from 758 reviews, recent review activity, a complete profile.
- 4.1 mi4.8(3,023)
PurLife Dispensary - Las Cruces
4.83,023 Google reviews$755 S Telshor Blvd #102a, Las Cruces, New Mexico- dual
Ranks on 4.8-star average from 3023 reviews, recent review activity, a complete profile.
- 3.6 mi4.8(796)
Ranks on 4.8-star average from 796 reviews, recent review activity, a complete profile.
- 6.2 mi4.8(660)
Pecos Valley Production - Dispensary & Wholesale
4.8660 Google reviews$3050 Roadrunner Pkwy #2, Las Cruces, New Mexico- dual
Ranks on 4.8-star average from 660 reviews, recent review activity, a complete profile.
- 2.6 mi4.9(625)
Munchiez Cannabis Dispensary Las Cruces
4.9625 Google reviews$1201 S Solano Dr, Las Cruces, New Mexico- dual
Ranks on 4.9-star average from 625 reviews, recent review activity, a complete profile.
- 2.6 mi4.9(503)
Effy Exotics Dispensary & New 24hr Drive Thru
4.9503 Google reviews$2153 W Picacho Ave, Las Cruces, New Mexico- dual
Ranks on 4.9-star average from 503 reviews, a live menu on WeedDispos, recent review activity, a complete profile.
Carries Dime Industries, Bloom, Cure INJOY, Drool.
- 4.6 mi4.9(261)
Urban Wellness Cannabis Dispensary - Las Cruces
4.9261 Google reviews$3830 E Lohman Ave Bldg. 1, Suite 03, Las Cruces, New Mexico- dual
Ranks on 4.9-star average from 261 reviews, a live menu on WeedDispos, recent review activity, a complete profile.
Carries Wyld, Dime Industries, Wana Edibles, Airo Brands.
- 1.5 mi5.0(167)
Ranks on 5.0-star average from 167 reviews, recent review activity, a complete profile.
- 3.2 mi5.0(162)
Ranks on 5.0-star average from 162 reviews, recent review activity, a complete profile.
- 1.9 mi4.8(720)
Pharmtrue Cannabis Dispensary - Valley
4.8720 Google reviews$580 S Valley Dr Ste 300, Las Cruces, New Mexico- dual
Ranks on 4.8-star average from 720 reviews, recent review activity, a complete profile.
- 3.5 mi4.8(315)
Ranks on 4.8-star average from 315 reviews, a live menu on WeedDispos, recent review activity, a complete profile.
Carries Bonanza Cannabis Company, Sinful Beverages, Sublime.
- 5.4 mi4.8(537)
Ranks on 4.8-star average from 537 reviews, recent review activity, a complete profile.
- 3.6 mi4.9(272)
Ranks on 4.9-star average from 272 reviews, recent review activity, a complete profile.
- #14
Dreamz Dispensary - Medical & Recreational Marijuana Cannabis Dispensary Las Cruces, NM
4.8★ (374)Open nowWeedDispos Score 70/1003.0 mi4.8(374)
Dreamz Dispensary - Medical & Recreational Marijuana Cannabis Dispensary Las Cruces, NM
4.8374 Google reviews$140 W Picacho Ave Ste C, Las Cruces, New Mexico- dual
Ranks on 4.8-star average from 374 reviews, recent review activity, a complete profile.
- 6.7 mi4.8(336)
Amigos Cannabis Dispensary - Las Cruces
4.8336 Google reviews$3330 Rinconada Blvd Ste 1, Las Cruces, New Mexico- dual
Ranks on 4.8-star average from 336 reviews, a live menu on WeedDispos, recent review activity, a complete profile.
Carries Wyld, Dime Industries, Wana Edibles, Clipper.
- 2.7 mi5.0(150)
Ranks on 5.0-star average from 150 reviews, recent review activity, a complete profile.
- 6.7 mi4.9(260)
Canna Company- Las Cruces Dispensary
4.9260 Google reviews$3510 Northrise Dr suite 4, Las Cruces, New Mexico- dual
Ranks on 4.9-star average from 260 reviews, recent review activity.
- 2.9 mi4.5(882)
Pecos Valley Production - Dispensary & Wholesale
4.5882 Google reviews$2460 S Locust St Ste 1, Las Cruces, New Mexico- dual
Ranks on 4.5-star average from 882 reviews, recent review activity, a complete profile.
- 2.1 mi4.7(147)
Ranks on 4.7-star average from 147 reviews, recent review activity, a complete profile.
- 8.1 mi4.8(200)
Ranks on 4.8-star average from 200 reviews, a live menu on WeedDispos, recent review activity, a complete profile.
- 4.1 mi4.5(507)
R.Greenleaf Las Cruces - Cannabis Dispensary
4.5507 Google reviews$775 S Telshor Blvd, Las Cruces, New Mexico- dual
Ranks on 4.5-star average from 507 reviews, recent review activity, a complete profile.
- 3.1 mi4.8(252)
Ranks on 4.8-star average from 252 reviews, recent review activity.
- 2.7 mi5.0(81)
Simply Baked
5.081 Google reviews$Inside "Grounded" Court Yard, 300 N Main St suite #4, Las Cruces, New Mexico- dual
Ranks on 5.0-star average from 81 reviews, a live menu on WeedDispos, recent review activity, a complete profile.
Carries Wyld, Dime Industries, Wana Edibles, Airo Brands.
- 1.2 mi4.7(240)
Ranks on 4.7-star average from 240 reviews, recent review activity, a complete profile.
- 2.7 mi4.8(75)
Ranks on 4.8-star average from 75 reviews, recent review activity, a complete profile.
- 7.4 mi4.7(101)
Everest Las Cruces North
4.7101 Google reviews$4165 White Sage Arc Ste D, Las Cruces, New Mexico- dual
Ranks on 4.7-star average from 101 reviews, recent review activity, a complete profile.
- 3.1 mi4.7(95)
Ranks on 4.7-star average from 95 reviews, recent review activity, a complete profile.
- 2.6 mi4.6(134)
Ranks on 4.6-star average from 134 reviews, recent review activity, a complete profile.
- 3.1 mi4.8(87)
Yucca Point Dispensary City of Las Cruces
4.887 Google reviews$1000 N Main St Suite A, Las Cruces, New Mexico- dual
Ranks on 4.8-star average from 87 reviews, a live menu on WeedDispos, recent review activity, a complete profile.
Carries Crystal Collection.
- 2.5 mi4.8(202)
Ranks on 4.8-star average from 202 reviews, recent review activity, a complete profile.
What to know about buying weed in Mesilla
Mesilla has 56 licensed dispensaries within a 20-mile drive of the city centre. Bring valid photo ID; licence types vary store to store. Across Mesilla, New Mexico, verified reviews average 4.8★.
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How we rank
The WeedDispos Score is a 0–100 composite built only from data we already store for each licensed shop: review rating (Bayesian-adjusted so a 5.0 from three reviews cannot outrank a 4.8 from two thousand), review volume on a log scale, how recent those reviews are, listing completeness, verified status, whether we have a live product menu, and photo coverage. Signals we do not have for a store are dropped and the remaining weights are re-normalized, so nothing is penalized for missing third-party data. Scores refresh nightly. Ranking is never for sale.
- 35% Rating quality (Bayesian-adjusted)
- 20% Review volume (log-scaled)
- 12% Listing completeness
- 10% Review freshness
- 8% Verified listing
- 8% Live menu available
- 7% Photo coverage
Frequently asked questions
How many dispensaries are there in Mesilla, New Mexico?
We track 56 licensed cannabis dispensaries in and around Mesilla, New Mexico. This page ranks the top 30; the full Mesilla directory lists every store.
What is the highest rated dispensary in Mesilla?
Akeso Botanicals LLC holds the highest verified rating in Mesilla, New Mexico at 5.0★ from 167 reviews.
Which Mesilla dispensary is cheapest?
Greene Street Weed Dispensary reports the lowest price band we have on file in Mesilla, New Mexico ($). Menu prices change daily, so compare the live menus before you drive.
Are any Mesilla dispensaries open late?
30 of the ranked Mesilla stores publish their opening hours with us, so you can check tonight's closing time on each listing before heading over.
Is there weed delivery in Mesilla?
Some Mesilla, New Mexico stores deliver. Check the delivery badge on each listing, or open the Mesilla directory to filter for shops that deliver.
How are the best dispensaries in Mesilla ranked?
The WeedDispos Score is a 0–100 composite built only from data we already store for each licensed shop: review rating (Bayesian-adjusted so a 5.0 from three reviews cannot outrank a 4.8 from two thousand), review volume on a log scale, how recent those reviews are, listing completeness, verified status, whether we have a live product menu, and photo coverage. Signals we do not have for a store are dropped and the remaining weights are re-normalized, so nothing is penalized for missing third-party data. Scores refresh nightly. Ranking is never for sale.