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Main Street Cannabis — Dispensary in Pine Ridge, South Dakota

99 E Main St, Pine Ridge, South Dakota 57770

4.7· 81 reviews

Ranked #3 of the best dispensaries in Pine Ridge · WeedDispos Score 62/100 →

dual

Overview

Main Street Cannabis is a dual dispensary located at 99 E Main St in Pine Ridge, South Dakota. The business holds a 4.7 rating based on 81 Google reviews. This establishment features an affordable price range and operates seven days a week. Customers can visit from 8:00 a.m. until 10:00 p.m. Monday through Saturday, with adjusted Sunday hours from 10:00 a.m. to 8:00 p.m.

4.7 (81 reviews) +1605-867-1892

Main Street Cannabis is a licensed cannabis dispensary in Pine Ridge, South Dakota, rated 4.7 out of 5 across 81 Google reviews, serving dual customers.

Main Street Cannabis — quick answers

Is Main Street Cannabis a good dispensary?
Main Street Cannabis holds a 4.7-star rating across 81 reviews in Pine Ridge, South Dakota, which places it among the highest-rated dispensaries in its market.
Where is Main Street Cannabis located?
Main Street Cannabis is at 99 E Main St, Pine Ridge, South Dakota 57770.
What is the phone number for Main Street Cannabis?
You can reach Main Street Cannabis at +1605-867-1892. Call ahead to confirm same-day stock and pickup windows.
Does Main Street Cannabis have an online menu?
Yes. Main Street Cannabis publishes a live menu with current products and pricing, updated by the store itself.

Reviews across the web

Google

4.7(81)

Ratings are shown per platform and are never combined into a single score.

About Main Street Cannabis

Located at 99 E Main St in Pine Ridge, South Dakota, Main Street Cannabis is a dual dispensary. This establishment carries various cannabis products and is categorized within an affordable price range. The store is open Monday through Saturday from 8:00 a.m. to 10:00 p.m. and on Sundays from 10:00 a.m. to 8:00 p.m. It has received 81 reviews.

About Main Street Cannabis in Pine Ridge, South Dakota

Inside the Pine Ridge market, Main Street Cannabis operates under South Dakota dual licensing — a meaningful distinction for shoppers who want compliant, tested product instead of the gray market. The shop is positioned for Pine Ridge residents picking up after work as well as travelers passing through who want a quick, legal stop before heading on. Shoppers report a typical price range of $ on regular menu items.

Why visit Main Street Cannabis

Regulars choose Main Street Cannabis for a strong 4.7 star average across 81 customer reviews, a typical price range of $, and a published phone line so you can confirm stock before driving over. As a dual retailer, the shop is meant for any qualifying customer per state law, and the staff is used to walking newcomers through dosing, onset times, and what to expect from different product formats.

What to expect at Main Street Cannabis

When you arrive at 99 E Main St, expect a standard ID check at the door — this is a regulated South Dakota cannabis dispensary, not a smoke shop. Posted hours are listed in the schedule below; it's smart to leave a buffer near closing time so budtenders can finish your order properly.

Cannabis in Pine Ridge, South Dakota

If you're new to Pine Ridge, South Dakota, Main Street Cannabis is a reasonable first stop for anyone who wants to see what a compliant dual dispensary actually looks like — clean displays, sealed packaging, certificates of analysis on request.

Planning a trip to Main Street Cannabis? Pine Ridge shoppers tend to bundle a stop here with errands nearby, so it pays to check live menu availability before you go — a quick call to +1605-867-1892 confirms what's actually in the case today. South Dakota law requires valid ID at entry, posted purchase limits at the register, and child-resistant exit packaging, all of which Main Street Cannabis follows as a licensed dual retailer.

See more options on the Pine Ridge dispensary directory or browse the full South Dakota dispensary list.

If you're exploring more options around Pine Ridge, you can also compare No Worries Dispensary in Pine Ridge, Warpath Cannabis in Pine Ridge or Warpath Cannabis in Pine Ridge on Weed Dispos.

Hours

Monday8:00 AM – 10:00 PM
Tuesday8:00 AM – 10:00 PM
Wednesday8:00 AM – 10:00 PM
Thursday8:00 AM – 10:00 PM
Friday8:00 AM – 10:00 PM
Saturday8:00 AM – 10:00 PM
Sunday10:00 AM – 8:00 PM

Location

Get directions to Main Street Cannabis

Menu

Full Menu

Browse Main Street Cannabis's live menu with current products and pricing.

WMView Full Menu on Weedmaps →

Reviews of Main Street Cannabis

3.9from 12 on-site reviews

Google: 4.7 · 81 reviews

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  • Jonas Jacobs
    June 28, 2026

    Doors were closed and locked during business hours. Checked online and said open. It wasn't.

  • N1NJabug650 12345
    May 5, 2026

    Really nice and clean establishment. If you’re into I would highly recommend it

  • Nathan S.
    September 18, 2025

    I bought 2 carts and they both stopped working after 5 hits. Complete waste of money. I bought a gram of wax there and that was good quality with a really good taste. A bit pricey. I don't think I'll be going back though

  • John YH
    September 6, 2025

    I'm going back

  • John Escott
    July 12, 2025

    Spectacular customer service and amazing inventory. Highly recommend staff and services available!

Frequently Asked Questions

What kind of dispensary is Main Street Cannabis?
Main Street Cannabis is a dual cannabis dispensary in Pine Ridge, South Dakota (ZIP 57770). It serves customers eligible under current state law.
Where exactly is Main Street Cannabis located?
Main Street Cannabis is located at 99 E Main St, Pine Ridge, South Dakota, 57770. Use the map on this page to get driving directions from anywhere in Pine Ridge.
What are the hours at Main Street Cannabis?
Current opening hours are listed in the Hours section above — check the day you plan to visit and leave time before close so budtenders can complete your order.
Does Main Street Cannabis offer delivery or pickup in Pine Ridge?
Delivery and pickup options vary by week. The fastest way to confirm is to call +1605-867-1892.
Is Main Street Cannabis a good fit for first-time cannabis buyers?
Yes — a licensed dual dispensary like Main Street Cannabis is exactly where new Pine Ridge, South Dakota consumers should start. Budtenders are trained to ask about your experience level, recommend low-dose products, and explain onset time and duration for edibles vs. inhaled formats.
How can I contact Main Street Cannabis?
Phone: +1605-867-1892. Or visit in person at 99 E Main St, Pine Ridge, South Dakota.

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