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Cannabis Headquarters — Dispensary in Tupelo, Mississippi

608 N Gloster St, Tupelo, Mississippi 38804

5.0· 272 reviews

Ranked #1 of the best dispensaries in Tupelo · WeedDispos Score 74/100 →

dual

Overview

Cannabis Headquarters is a dual dispensary located at 608 N Gloster St in Tupelo, Mississippi. The business maintains a 5-star rating from 272 Google reviews, a 4.7 rating from 521 Weedmaps reviews, and a 5-star rating from 51 Leafly reviews. Shoppers can access this location Monday through Saturday from 8:00 AM until midnight, and on Sundays from 10:00 AM until 8:00 PM. The shop falls into the lowest price category.

5.0 (272 reviews) (662) 269-2070 Website

Cannabis Headquarters is a licensed cannabis dispensary in Tupelo, Mississippi, rated 5.0 out of 5 across 272 Google reviews, serving dual customers.

Cannabis Headquarters — quick answers

Is Cannabis Headquarters a good dispensary?
Cannabis Headquarters holds a 5.0-star rating across 272 reviews in Tupelo, Mississippi, which places it among the highest-rated dispensaries in its market.
Where is Cannabis Headquarters located?
Cannabis Headquarters is at 608 N Gloster St, Tupelo, Mississippi 38804.
What is the phone number for Cannabis Headquarters?
You can reach Cannabis Headquarters at (662) 269-2070. Call ahead to confirm same-day stock and pickup windows.
Does Cannabis Headquarters have an online menu?
Yes. Cannabis Headquarters publishes a live menu with current products and pricing, updated by the store itself.

Reviews across the web

Google

5.0(272)

Weedmaps

4.7(521)

Leafly

5.0(51)

Ratings are shown per platform and are never combined into a single score.

About Cannabis Headquarters

Cannabis Headquarters operates as a dual dispensary situated at 608 N Gloster St in Tupelo, Mississippi. This establishment is categorized in the lowest price range. The store is open Monday through Saturday from 8:00 AM to midnight, with Sunday hours running from 10:00 AM until 8:00 PM. It has received 272 reviews resulting in a 5 out of 5 rating.

About Cannabis Headquarters in Tupelo, Mississippi

Inside the Tupelo market, Cannabis Headquarters operates under Mississippi dual licensing — a meaningful distinction for shoppers who want compliant, tested product instead of the gray market. The shop is positioned for Tupelo residents picking up after work as well as travelers passing through who want a quick, legal stop before heading on. Shoppers report a typical price range of $ on regular menu items.

Why visit Cannabis Headquarters

Regulars choose Cannabis Headquarters for a strong 5.0 star average across 272 customer reviews, a typical price range of $, a published phone line so you can confirm stock before driving over, and a public website with additional menu details. As a dual retailer, the shop is meant for any qualifying customer per state law, and the staff is used to walking newcomers through dosing, onset times, and what to expect from different product formats.

What to expect at Cannabis Headquarters

When you arrive at 608 N Gloster St, expect a standard ID check at the door — this is a regulated Mississippi cannabis dispensary, not a smoke shop. Posted hours are listed in the schedule below; it's smart to leave a buffer near closing time so budtenders can finish your order properly.

Cannabis in Tupelo, Mississippi

For travelers passing through Tupelo, Mississippi, Cannabis Headquarters is a convenient brick-and-mortar option that follows Mississippi possession limits and ID requirements you'll want to know before you buy.

Planning a trip to Cannabis Headquarters? Tupelo shoppers tend to bundle a stop here with errands nearby, so it pays to check live menu availability before you go — a quick call to (662) 269-2070 confirms what's actually in the case today. Mississippi law requires valid ID at entry, posted purchase limits at the register, and child-resistant exit packaging, all of which Cannabis Headquarters follows as a licensed dual retailer.

See more options on the Tupelo dispensary directory or browse the full Mississippi dispensary list.

If you're exploring more options around Tupelo, you can also compare CannaCare Dispensary in Tupelo, High Hopes in Tupelo or Bragg Canna (Tupelo) in Tupelo on Weed Dispos.

Hours

Monday8:00 AM – 12:00 AM
Tuesday8:00 AM – 12:00 AM
Wednesday8:00 AM – 12:00 AM
Thursday8:00 AM – 12:00 AM
Friday8:00 AM – 12:00 AM
Saturday8:00 AM – 12:00 AM
Sunday10:00 AM – 8:00 PM

Location

Get directions to Cannabis Headquarters

License, verification & services

Info verified October 18, 2026

Menu

Full Menu

Browse Cannabis Headquarters's live menu with current products and pricing.

4.7on Weedmaps · 521 reviews

WMView Full Menu on Weedmaps →

Reviews of Cannabis Headquarters

4.9from 15 on-site reviews

Google: 5.0 · 272 reviews

5★
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  • deonte corrie
    July 17, 2026

    Great deals great people i love this place!

  • Kim
    July 7, 2026

    Greta is fantastic

  • Stephen Austin
    June 29, 2026

    GREDA IS THE BEST WEED DUDE EVER!

  • J p R
    June 23, 2026

    Bud tenders are awesome great selection... Wide variety of products very trustworthy store .There's 1 lady that's very friendly and knowledgeable she's the greatest

  • Jennifer Ray
    June 22, 2026

    Great customer service and products. My favorite store in Tupelo and they're open late yay 🥰👏👏👏.

Frequently Asked Questions

What kind of dispensary is Cannabis Headquarters?
Cannabis Headquarters is a dual cannabis dispensary in Tupelo, Mississippi (ZIP 38804). It serves customers eligible under current state law.
Where exactly is Cannabis Headquarters located?
Cannabis Headquarters is located at 608 N Gloster St, Tupelo, Mississippi, 38804. Use the map on this page to get driving directions from anywhere in Tupelo.
What are the hours at Cannabis Headquarters?
Current opening hours are listed in the Hours section above — check the day you plan to visit and leave time before close so budtenders can complete your order.
Does Cannabis Headquarters offer delivery or pickup in Tupelo?
Delivery and pickup options vary by week. The fastest way to confirm is to call (662) 269-2070.
Is Cannabis Headquarters a good fit for first-time cannabis buyers?
Yes — a licensed dual dispensary like Cannabis Headquarters is exactly where new Tupelo, Mississippi consumers should start. Budtenders are trained to ask about your experience level, recommend low-dose products, and explain onset time and duration for edibles vs. inhaled formats.
How can I contact Cannabis Headquarters?
Phone: (662) 269-2070. Website: https://cannabisheadquarter.com/. Or visit in person at 608 N Gloster St, Tupelo, Mississippi.

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