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High Desert Relief Cannabis Dispensary — Dispensary in Santa Fe, New Mexico

5041 Main St #102, Santa Fe, New Mexico 87507

4.8· 313 reviews

Ranked #2 of the best dispensaries in Santa Fe · WeedDispos Score 71/100 →

dual

Overview

High Desert Relief Cannabis Dispensary is a dual-use cannabis store located at 5041 Main St #102 in Santa Fe, New Mexico. The business holds a 4.8-star rating based on feedback from 313 Google reviewers. Visitors will find that the establishment maintains a consistent daily schedule, remaining open from 9:00 a.m. until 9:00 p.m. throughout the entire week. The dispensary is categorized within an affordable price range for its customers.

4.8 (313 reviews) +1505-750-0608 Website

High Desert Relief Cannabis Dispensary is a licensed cannabis dispensary in Santa Fe, New Mexico, rated 4.8 out of 5 across 313 Google reviews, serving dual customers.

High Desert Relief Cannabis Dispensary — quick answers

Is High Desert Relief Cannabis Dispensary a good dispensary?
High Desert Relief Cannabis Dispensary holds a 4.8-star rating across 313 reviews in Santa Fe, New Mexico, which places it among the highest-rated dispensaries in its market.
Where is High Desert Relief Cannabis Dispensary located?
High Desert Relief Cannabis Dispensary is at 5041 Main St #102, Santa Fe, New Mexico 87507.
What is the phone number for High Desert Relief Cannabis Dispensary?
You can reach High Desert Relief Cannabis Dispensary at +1505-750-0608. Call ahead to confirm same-day stock and pickup windows.
Does High Desert Relief Cannabis Dispensary have an online menu?
Yes. High Desert Relief Cannabis Dispensary publishes a live menu with current products and pricing, updated by the store itself.

Reviews across the web

Google

4.8(313)

Ratings are shown per platform and are never combined into a single score.

About High Desert Relief Cannabis Dispensary

Located at 5041 Main St #102 in Santa Fe, New Mexico, High Desert Relief Cannabis Dispensary operates as a dual-use facility. The shop is open daily from 9:00 a.m. to 9:00 p.m. Patrons can expect an affordable price range at this cannabis store, which has received a 4.8 out of 5 rating based on 313 reviews.

About High Desert Relief Cannabis Dispensary in Santa Fe, New Mexico

High Desert Relief Cannabis Dispensary serves Santa Fe, New Mexico as a dual cannabis dispensary, giving locals and visitors a regulated option without leaving town. The shop is positioned for Santa Fe residents picking up after work as well as travelers passing through who want a quick, legal stop before heading on. Shoppers report a typical price range of $ on regular menu items.

Why visit High Desert Relief Cannabis Dispensary

Regulars choose High Desert Relief Cannabis Dispensary for a strong 4.8 star average across 313 customer reviews, a typical price range of $, a published phone line so you can confirm stock before driving over, and a public website with additional menu details. As a dual retailer, the shop is meant for any qualifying customer per state law, and the staff is used to walking newcomers through dosing, onset times, and what to expect from different product formats.

What to expect at High Desert Relief Cannabis Dispensary

When you arrive at 5041 Main St #102, expect a standard ID check at the door — this is a regulated New Mexico cannabis dispensary, not a smoke shop. Posted hours are listed in the schedule below; it's smart to leave a buffer near closing time so budtenders can finish your order properly.

Cannabis in Santa Fe, New Mexico

For travelers passing through Santa Fe, New Mexico, High Desert Relief Cannabis Dispensary is a convenient brick-and-mortar option that follows New Mexico possession limits and ID requirements you'll want to know before you buy.

If you're comparing Santa Fe, New Mexico dispensaries, High Desert Relief Cannabis Dispensary is worth a look for shoppers who value a regulated, walk-in experience over delivery-only brands. With 313 customer reviews on file averaging 4.8 stars, you can get a sense of staff knowledge, wait times, and value before you decide. As always with cannabis, start low and slow with any new product format and follow New Mexico possession limits.

See more options on the Santa Fe dispensary directory or browse the full New Mexico dispensary list.

If you're exploring more options around Santa Fe, you can also compare Best Daze in Santa Fe, Verdes Cannabis - Santa Fe Zafarano in Santa Fe or Green Fuego in Santa Fe on Weed Dispos.

Hours

Monday9:00 AM – 9:00 PM
Tuesday9:00 AM – 9:00 PM
Wednesday9:00 AM – 9:00 PM
Thursday9:00 AM – 9:00 PM
Friday9:00 AM – 9:00 PM
Saturday9:00 AM – 9:00 PM
Sunday9:00 AM – 9:00 PM

Location

Get directions to High Desert Relief Cannabis Dispensary

License, verification & services

Info verified October 19, 2026

Menu

Full Menu

Browse High Desert Relief Cannabis Dispensary's live menu with current products and pricing.

View Full Menu →

Reviews of High Desert Relief Cannabis Dispensary

5.0from 15 on-site reviews

Google: 4.8 · 313 reviews

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  • Elizabeth Garcia
    July 27, 2026

    We loved our experience with Keaton. He was so helpful, knowledgeable, and kind! I can’t wait to visit with him again! Always helpful.

  • Roy Tiedeman
    July 26, 2026

    Keaton is amazing!!!!! Thanks

  • Rhoda Nunn
    July 26, 2026

    Love this spot!

  • Ian Riefner
    July 26, 2026

    Keaton solid bud tender

  • Mile TheHigh
    July 25, 2026

    Keaton was amazing bud tender, super chill, and helpful!

Frequently Asked Questions

What kind of dispensary is High Desert Relief Cannabis Dispensary?
High Desert Relief Cannabis Dispensary is a dual cannabis dispensary in Santa Fe, New Mexico (ZIP 87507). It serves customers eligible under current state law.
Where exactly is High Desert Relief Cannabis Dispensary located?
High Desert Relief Cannabis Dispensary is located at 5041 Main St #102, Santa Fe, New Mexico, 87507. Use the map on this page to get driving directions from anywhere in Santa Fe.
What are the hours at High Desert Relief Cannabis Dispensary?
Current opening hours are listed in the Hours section above — check the day you plan to visit and leave time before close so budtenders can complete your order.
Does High Desert Relief Cannabis Dispensary offer delivery or pickup in Santa Fe?
Delivery and pickup options vary by week. The fastest way to confirm is to call +1505-750-0608.
Is High Desert Relief Cannabis Dispensary a good fit for first-time cannabis buyers?
Yes — a licensed dual dispensary like High Desert Relief Cannabis Dispensary is exactly where new Santa Fe, New Mexico consumers should start. Budtenders are trained to ask about your experience level, recommend low-dose products, and explain onset time and duration for edibles vs. inhaled formats.
How can I contact High Desert Relief Cannabis Dispensary?
Phone: +1505-750-0608. Website: https://highdesertrelief.org/. Or visit in person at 5041 Main St #102, Santa Fe, New Mexico.

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