Weed Dispos

The Highest Care Dispensary — Dispensary in Natchez, Mississippi

2 Sgt Prentiss Dr, Natchez, Mississippi 39120

5.0· 120 reviews

Best Dispensaries in Natchez · WeedDispos Score 77/100 →

dual

Overview

The Highest Care Dispensary is a dual-licensed facility located at 2 Sgt Prentiss Dr in Natchez, Mississippi. This business holds a 5-star rating based on 120 Google reviews, 512 Weedmaps reviews, and 520 Leafly reviews. Customers can purchase products from brands including Delta Bud Company, Green Hornet, Major, High Hemp, Pharm Grown Canna Company, Southern Sky Brands, Wana Edibles, MidSouth Extracts, Noble Labs, and Drool. The shop is open daily, closing at 4:00 p.m. on Sundays and 6:00 p.m. on all other days.

5.0 (120 reviews) +1769-376-5022 Website

The Highest Care Dispensary is a licensed cannabis dispensary in Natchez, Mississippi, rated 5.0 out of 5 across 120 Google reviews, serving dual customers.

The Highest Care Dispensary — quick answers

Is The Highest Care Dispensary a good dispensary?
The Highest Care Dispensary holds a 5.0-star rating across 120 reviews in Natchez, Mississippi, which places it among the highest-rated dispensaries in its market.
Where is The Highest Care Dispensary located?
The Highest Care Dispensary is at 2 Sgt Prentiss Dr, Natchez, Mississippi 39120.
What is the phone number for The Highest Care Dispensary?
You can reach The Highest Care Dispensary at +1769-376-5022. Call ahead to confirm same-day stock and pickup windows.
Does The Highest Care Dispensary have an online menu?
Yes. The Highest Care Dispensary publishes a live menu with current products and pricing, updated by the store itself.

Reviews across the web

Google

5.0(120)

Weedmaps

5.0(512)

Leafly

5.0(520)

Ratings are shown per platform and are never combined into a single score.

About The Highest Care Dispensary

The Highest Care Dispensary operates as a dual-licensed cannabis store at 2 Sgt Prentiss Dr in Natchez, Mississippi. Inventory includes products from Delta Bud Company, Green Hornet, Major, High Hemp, Pharm Grown Canna Company, Southern Sky Brands, Wana Edibles, and MidSouth Extracts. This location welcomes visitors Monday through Saturday from 10:00 to 18:00, and on Sunday from 10:00 to 16:00.

About The Highest Care Dispensary in Natchez, Mississippi

The Highest Care Dispensary's Natchez, Mississippi storefront sits inside Mississippi's regulated dual program, with seed-to-sale tracked inventory and posted retail hours. The shop is positioned for Natchez residents picking up after work as well as travelers passing through who want a quick, legal stop before heading on. Shoppers report a typical price range of $ on regular menu items.

Why visit The Highest Care Dispensary

Regulars choose The Highest Care Dispensary for a strong 5.0 star average across 120 customer reviews, a typical price range of $, a published phone line so you can confirm stock before driving over, and a public website with additional menu details. As a dual retailer, the shop is meant for any qualifying customer per state law, and the staff is used to walking newcomers through dosing, onset times, and what to expect from different product formats.

What to expect at The Highest Care Dispensary

When you arrive at 2 Sgt Prentiss Dr, expect a standard ID check at the door — this is a regulated Mississippi cannabis dispensary, not a smoke shop. Posted hours are listed in the schedule below; it's smart to leave a buffer near closing time so budtenders can finish your order properly.

Cannabis in Natchez, Mississippi

If you're new to Natchez, Mississippi, The Highest Care Dispensary is a reasonable first stop for anyone who wants to see what a compliant dual dispensary actually looks like — clean displays, sealed packaging, certificates of analysis on request.

For Natchez regulars, The Highest Care Dispensary fits into the broader Mississippi cannabis landscape as a compliant dual option with seed-to-sale traceability and lab-tested SKUs. and the menu rotates often enough that even regulars usually find something new on the shelf — new strain drops, fresh concentrate batches, or limited edible runs from in-state brands.

See more options on the Natchez dispensary directory or browse the full Mississippi dispensary list.

If you're exploring more options around Natchez, you can also compare Star Buds Medical Cannabis Dispensary Natchez in Natchez, Toke and Tell in Natchez or Loaded Flower Cannabis Dispensary in Natchez on Weed Dispos.

Hours

Monday10:00 AM – 6:00 PM
Tuesday10:00 AM – 6:00 PM
Wednesday10:00 AM – 6:00 PM
Thursday10:00 AM – 6:00 PM
Friday10:00 AM – 6:00 PM
Saturday10:00 AM – 6:00 PM
Sunday10:00 AM – 4:00 PM

Location

Get directions to The Highest Care Dispensary

License, verification & services

Info verified October 18, 2026

Full Menu

Browse The Highest Care Dispensary's live menu with current products and pricing.

5.0on Weedmaps · 512 reviews

WMView Full Menu on Weedmaps →

Reviews of The Highest Care Dispensary

5.0from 15 on-site reviews

Google: 5.0 · 120 reviews

5★
15
4★
0
3★
0
2★
0
1★
0
  • charles walters
    May 5, 2026

    Nice Quality Products

  • Janet Jackson
    April 30, 2026

    Very friendly and helpful.

  • Alfred Galtney
    April 30, 2026

    My mom has pain as well as the elderly in my community they have truly helped me identify rubs that soothes arthritis and very knowledgeable about components to help alleviate pain that is derived from the plant

  • Michael Burris
    April 30, 2026

    Come and sign up and get knowledgeable information on what they carry on the products

  • C
    April 30, 2026

    THC is everything you want in a dispensary. Great deals, high quality product and a warm and inviting atmosphere with super nice, knowledgeable staff who know their product. This is the spot, Get there. You'll be glad you did.

Frequently Asked Questions

What kind of dispensary is The Highest Care Dispensary?
The Highest Care Dispensary is a dual cannabis dispensary in Natchez, Mississippi (ZIP 39120). It serves customers eligible under current state law.
Where exactly is The Highest Care Dispensary located?
The Highest Care Dispensary is located at 2 Sgt Prentiss Dr, Natchez, Mississippi, 39120. Use the map on this page to get driving directions from anywhere in Natchez.
What are the hours at The Highest Care Dispensary?
Current opening hours are listed in the Hours section above — check the day you plan to visit and leave time before close so budtenders can complete your order.
Does The Highest Care Dispensary offer delivery or pickup in Natchez?
Delivery and pickup options vary by week. The fastest way to confirm is to call +1769-376-5022.
Is The Highest Care Dispensary a good fit for first-time cannabis buyers?
Yes — a licensed dual dispensary like The Highest Care Dispensary is exactly where new Natchez, Mississippi consumers should start. Budtenders are trained to ask about your experience level, recommend low-dose products, and explain onset time and duration for edibles vs. inhaled formats.
How can I contact The Highest Care Dispensary?
Phone: +1769-376-5022. Website: http://www.thehighestcare.com/. Or visit in person at 2 Sgt Prentiss Dr, Natchez, Mississippi.
What products can you buy at The Highest Care Dispensary?
The Highest Care Dispensary's current menu on this page lists 240 items, including products from Delta Bud Company, Green Hornet, Major, High Hemp and Pharm Grown Canna Company. Prices reflect the store's most recent menu sync.

Brands carried at The Highest Care Dispensary

Each link shows where to buy that brand in Natchez.

Nearby Dispensaries

More cannabis pages for Natchez, Mississippi

More dispensaries in Natchez

Prices, deals & delivery near Natchez

Call The Directions